MORE great reasons to take Over-the-Counter (OTC) Pregnenolone
To read the article, here.
Commentary by Dr. John Crisler on December 12, 2017
This is a great magazine article. In my experience, the same applies to men.
Although it mentions the hormone Progesterone as a source, Allopregnanolone (Allo) also comes from a hormone further upstream in the natural pathways, called Pregnenolone (PREG). I use Progesterone only in my female patients, but not adult males; for them, it is quite feminizing. But I often recommend PREG to patients of all genders.
PREG is known as the “grandmother of all hormones”, in that it is first in the metabolic pathways after Cholesterol. It is naturally found in every cell in the body, and so is part of my strategy of “Backfilling the Pathways” in restoring normal function in my patients with hormonal imbalances (including those caused by treatment with Testosterone Replacement Therapy).
Much of Pregnenolone’s benefits are because it is converted in the body to Allo, which is like Nature’s benzodiazepine (i.e. Valium, Xanax, Ativan). That is why it can be so effective (and safe!), for treating serious issues such as anxiety, and depression. In fact, Pregnenolone was routinely—and very effectively—employed to treat anxiety, depression, and adrenal insufficiency in the United States in the 1930’s and 40’s. That was before BigPharma took over.
Pregnenolone, for the same reasons, and pathways, is now used extensively by cutting edge doctors in treating Traumatic Brain Injury (TBI).
During my medical career, I’ve had two patients tell me oral PREG made their stuttering go away. As you can guess, stuttering and anxiety are closely related. I knew it was working, because I was talking to them.
You can take Pregnenolone mixed in a cream you apply to your skin, which we have made up for our patients by our favorite compounding pharmacy, Empower Pharmacy. But you can also get oral capsules from them, of which the SR (Sustained Release) form are the best. Creams and SR oral preparations provide slow, steady administration into the body.
To treat anxiety with oral PREG (hopefully, the Sustained Release version), take right before going to bed at night. We usually start with 30-50mg. IF you are not groggy in the morning, and are still suffering anxiety during the day, try taking a similar dose with breakfast. Some people can only tolerate 10mg, once per day. Others use as much as 300mg per day, in divided doses. Is PREG powerful? I’ve seen people go into a stupor on fairly low doses…don’t drive or operate machinery until you have tried it safely.
Many, many patients have told me, over my 16 years of clinical practice, PREG had a large impact on their life. We use a number of different protocols with it, depending upon the patient’s specific case.
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Contact us now for an appointment to talk to one of the most experienced professionals in Age-Management Medicine for men and women. Dr. John Crisler – (517) 485-4424 or click HERE to email us.